Yes, bed bugs can easily spread to other rooms in a house. They are adept at hitchhiking on clothing, luggage, furniture, and other items that are moved from one room to another. Additionally, bed bugs can travel through small spaces and cracks in walls, floors, and ceilings, enabling them to move between adjacent rooms or apartments. Their small size and flat bodies make it easy for them to hide and be inadvertently transported, increasing the risk of spreading throughout a home. Regular inspection and cleanliness can help prevent their spread, but professional extermination is often necessary if an infestation occurs.